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What are genetics & how does sickle cell disease affect a person

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How likely a person is to develop sickle cell disease? How is it passed from parent to child? What do genes have to do with a person's traits?

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This discussed how genetics can affect a person and how likely a person is to develop sickle cell disease.

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Exactly what is in a person's genes? What are genetics? How can parents influence the traits of their children? Who is likely to develop a disease such as Sickle cell disease? These are questions that so many people may ask if their child has been diagnosed with a genetic disease. In this paper, I will discuss how genetics affect development, how parents can influence the trait of sickle cell disease and how sickle cell disease is affected by genetics and chromosomal disorders.

The human body is made up of cells that contain DNA which bond together to form 23 pairs of chromosomes (Mossler, 2011). Half of the chromosomes in a person's body come from the mother and the other half come from the father. Genes are located on chromosomes and consist of DNA which we inherit from our parents (Mayo Clinic, 2011). These genes contain specific instructions as to what a person's characteristics we will be such as: eye color, hair color, height, weight, and in some cases health (Mayo Clinic, 2011). Genes that are inherited from parents can also be linked to diseases as well as traits.

Mutation in the HBB gene cause sickle cell disease which is an inherited blood disorder that encodes for the protein hemoglobin (Sickle cell disease, 2012). Hemoglobin is the protein that carries oxygen to the tissues in the body (Sickle cell disease, 2012). This genetic mutation causes the hemoglobin protein to become sticky on the protein surface which causes the molecules to stick together forming log fibers (Sickle cell disease, 2012). These fibers or rods, distort the shape of the red blood cells into sickle shaped which impedes the travel of the red blood cells and can cause ...

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  • A.S., Oklahoma State University
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