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    Water solubility of secondary messengers

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    Is it true that all small intracellular mediators (second messengers) are water-soluble and pass freely through the cytosol? Why?

    I know this is true, but why is it true?

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    Well, all of the cytosolic second messengers that I can think of off the top of my head are certainly water-soluble and pass freely through the cytosol, e.g. cyclic AMP, Ca ions, inositol triphosphate, etc.

    Why would this be ...

    Solution Summary

    The expert examines water solubility of secondary messengers. Water-solubility of passing through cytosol are determined.