Is it true that all small intracellular mediators (second messengers) are water-soluble and pass freely through the cytosol? Why?
I know this is true, but why is it true?
Well, all of the cytosolic second messengers that I can think of off the top of my head are certainly water-soluble and pass freely through the cytosol, e.g. cyclic AMP, Ca ions, inositol triphosphate, etc.
Why would this be ...