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Structure and Functions of Ribosomes

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Describe the main features of the ribosome structure in prokaryotes and eukaryotes. How can these differences be exploited to treat disease?

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Structure and functions of ribosomes are the basis for antibiotic intervention.

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Ribosomes are small (20 X 30 nm) approximately spherical ribonucleoprotein particles. The ribosome is made up of two subunits - the large (A) and the small subunit (B). A Yale University research group, headed by Thomas Steitz, determined the structure of the large subunit. This subunit is composed primarily of two long RNA molecules, a genetic material similar to DNA and found in all cells and some ...

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