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1. In an inherited condition called glycogen cardiomyopthy teenagers develop muscle weakness which affects heart as well as other muscles. Samples of the affected muscle cells contain huge lysosomes, swollen with the carbohydrate glycogen. How might this condition arise?

2. Why does a muscle cell conatin many mitochondrion while a white blood cell contain many lysosomes?

3. Exposure to tobacco smoke immobilizes cilia and they eventually disappear. How might this effect explain why smokers have an increased incidence of coughing and respiratory infections?

4. What is the cellular difference between a prokaryote and eukaryote?

5. Why are cells small?

6. What are the advantages and disadvantages of the light, scanner and trasmission electron microscopes?

7. How do microscopes help us study cells?

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1. In an inherited condition called glycogen cardiomyopathy teenagers develop muscle weakness which affects heart as well as other muscles. Samples of the affected muscle cells contain huge lysosomes, swollen with the carbohydrate glycogen. How might this condition arise?

This kind of cardiomyopathy is as example of a glycogen storage disease. Glycogen storage diseases involve altered metabolism of glycogen due to an enzyme deficiency.

Glycogen is stored in muscle fibers (glycogen can be broken down by enzymes into glucose for the muscle to use as energy). Therefore, if there is a deficiency of the enzyme that breaks down glycogen in the muscle (such as glycogen phosphorylase), the glycogen will build up.

In this disease, glycogen can't be converted into energy, so people who have it suffer muscle pain, cramping, and fatigue, as well as muscle wasting and cardiomyopathy.

2. Why does a muscle cell contain many mitochondria while a white blood cell contains many lysosomes?

This has to do with the function of each type of cell.

Muscle cells specialize in being able to contract, and they function to move the body and pump blood and other fluids. To do these jobs, and to contract when necessary, muscle cells need a lot of ATP (ATP ...

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