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Erythrocyte Sedimentation Rate (ESR) Questions

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See the attached file.
1. What is the purpose of the ESR assay?
2. State the normal range for ESR in (state reporting units)
Men? Women?
3. State the specimen requirement for ESR and time limits for performing the test.
4. What is the required time for performing a sed rate or ESR?
5. List the 4 sources of technical errors and describe the results when these errors occur.
In other words, is the ESR increased or decreased as a result of the error?
6. List the RBC factors and describe their effects on the ESR.
7. List the plasma factors and describe their effects on the ESR.
8. Is the ESR increased or decreased or normal in the following conditions?
A. Sickle cells present
b. Increased room temperature
C. Unlevel ESR rack
D. Nearby centrifuge in use
E. Elevated plasma immunoglobulin
F. Rouleaux
G. Disseminated intravascular coagulation
H. PID (pelvic inflammatory disease)
I. Appendicitis
J. Osteoarthritis
K. Rheumatoid arthritis
L. Ectopic pregnancy

9. What is the name of the ESR method that the Westergren method replaced?

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Solution Summary

The solution discusses various detailed questions regarding the erythrocyte sedimentation rate (ESR). range,

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1. What is the purpose of the ESR assay?
It is a non-specific test used to measure inflammation and is elevated in chronic inflammation whereas C-reactive protein (CRP) is elevated in acute inflammation. Together they provide a more sensitive measure of inflammation but specificity is low.

2 .State the normal range for ESR in (state reporting units)
Since the ESR increases with age, normal values also change. At 20, ESR = 12 mm/hr for men and 18 mm/hr for women; age 55, 14 mm/hr in men and 21 mm/hr in women; and at 90, 19 mm/hr in men and 23 mm/hr in women.
Normal in a newborn is 0-2 mm/hr and neonatal to puberty = 3 - 13 mm/hr.

3.State the specimen requirement for ESR and time limits for performing the test.
Specimen is obtained by venipuncture with tripotassium (K3) EDTA or sodium citrate tubes. The former is more reliable than the latter. The tubes are rotated gently ...

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