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VO2 max and functional capacities of physiological systems

In what specific ways would VO2 Max provide important insights about the functional capacities of diverse physiological systems?

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VO2 max of an individual will be entrained to the proper functioning of multiple systems. The breakdown of any one of them will negatively impact on maximal oxygen consumption (although some more than others).
<br>1) Lungs
<br> - lung volume available for respiration (will be related to size of person, and if there are any disease processes)
<br> - Diffusion capacity in the lungs (decreased by decreasing surface area of alveoli or thickening of perfusion tissue as found in COPD or restrictive lung disease)
<br>2) Heart and ...