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    Pancreatitis and Peptic Ulcers

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    Differentiate between pancreatitis and peptic ulcer.

    Compare and contrast the pathophysiology, signs, and possible complications of pancreatitis and peptic ulcer.

    Discuss the treatments of pancreatitis and peptic ulcer.

    © BrainMass Inc. brainmass.com December 24, 2021, 10:27 pm ad1c9bdddf
    https://brainmass.com/health-sciences/topics-in-health-and-wellness/pancreatitis-peptic-ulcers-476620

    SOLUTION This solution is FREE courtesy of BrainMass!

    The difference between pancreatitis and a peptic ulcer ultimately lies in the pathophysiology of the two conditions. Peptic ulcers are sores in the lining of the digestive tract that manifest when parts of the digestive lining are eroded away. The most common places that they manifest are the stomach (gastric ulcer) and duodenum of the small intestine. What causes peptic ulcers are either specific bacteria, most often heliobacter pylori) and or the use of NSAIDS. Usually, the stomach is protected from ulcers by its intrinsic mucous producing lining, but sometimes areas usually covered by the mucous can become uncovered. This will lead to the acids within the digestive tract having access to the lining and eroding it to form an ulcer. Usually if treated, a peptic ulcer will clear up without any complications, but if it is left untreated, peptic ulcers can lead to infection, scarring in the GI lining, perforations, and/or internal bleeding. Usually, peptic ulcers will heal without medications, but when medicine is necessary, the treatment will depend on the underlying cause of the ulcer. For instance, if the peptic ulcer is caused by the excessive use of NSAIDS, the physician will stop the use of NSAIDS. Other causes of peptic ulcers will be treated by proton pump inhibitors to decrease the stomach's production of acid.

    Opposed to being an ulcer of the digestive tract, pancreatitis is the inflammation of the pancreas. The pancreas is a part of the GI system, but not part of the physical tube that food passes through as it moves from mouth to anus. In some ways, it is similar to a peptic ulcer because it is ultimately due to the enzymes of the body attacking the body itself to cause inflammation. In this case, it is the enzymes in the pancreas that become activated in the pancreas and damage the organ, causing the inflammation. Normally, these enzymes are inactive until they enter the GI tract through the Sphincter of Odi, but in the case of pancreatitis, these enzymes become dangerously activated within the pancreas. Pancreatitis is caused by alcoholism, gallstones, abdominal surgery, certain medications, cigarette smoking, cystic fibrosis, endoscopic retrograde cholangiopancreatography (ERCP), when used to treat gallstones, family history of pancreatitis, high calcium levels in the blood (hypercalcemia), high levels of parathyroid hormone in the blood (hyperparathyroidism), high triglyceride levels in the blood (hypertriglyceridemia), infection, injury to the abdomen, and pancreatic cancer. Chronic pancreatitis can lead to complications like scar tissue on pancreas. Scar tissue on the pancreas can cause it to lose its function. A nonfunctional pancreas can cause digestive problems because the proper digestive enzymes are not being released from the pancreas. Diabetes can also ensue because pancreatic beta cells secrete insulin. A pancreas not producing insulin can result in diabetes.

    Opposed to peptic ulcers which will usually clear up without intervention, pancreatitis is more severe and often needs hospitalization. The treatment will depend on the cause of the pancreatitis. If it is due to issues with the bile ducts and gall bladder, the gall bladder can be removed or the obstruction can be cleared. If gallstones are causing the issue, they can be removed. Also, the patient will be given medicine to stop the inflammation and to treat the pain. Patients may also be provided with supplemental enzymes that the pancreas is not producing.

    Reference:

    Information taken from UpToDate.

    This content was COPIED from BrainMass.com - View the original, and get the already-completed solution here!

    © BrainMass Inc. brainmass.com December 24, 2021, 10:27 pm ad1c9bdddf>
    https://brainmass.com/health-sciences/topics-in-health-and-wellness/pancreatitis-peptic-ulcers-476620

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