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I need to discuss the impact of each study limitation in this paper on the study results. I need to identify the major weaknesses in the study *not* acknowledged by the authors and then discuss *why* it weakens the study.

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Solution Summary

Detailed review of the impact, background, aim, method, and conclusion of a given article on the increased predisposition of psoriasis patients for myocardial infarct (heart attack) independent of other risk factors such as smoking, diet, alcohol abuse. Special attention is paid to the limitations and weaknesses of the study presented.

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Impact:
This article is a research study on the increased predisposition of psoriasis patients for myocardial infarct (heart attack) independent of other risk factors such as smoking, diet, alcohol abuse etc. This is a critical article because it shows a link between an auto-inflammatory disease and an increased likelihood of a condition that can be made worse by defects in immune responses and result in death.

Background:
Psoriasis is T-helper cell disease and such diseases are associated with a higher risk of heart disease like heart attacks (myocardial infarct is a ...

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