Purchase Solution

Genetic Variations

Not what you're looking for?

Ask Custom Question

1. Duchenne muscular dystrophy (DMD) is an X-linked disease for which prenatal diagnostic testing can be performed. Has prenatal genetic testing increased the detection rate of this disease, compared to prior diagnostic methods? If so, how? If not, why? In case the fetus is diagnosed with DMD and parents decide to terminate the pregnancy, are there chances that the next child will also be a carrier of the disease?

2. Jane Hill's husband, Charlie Marlow, has hemophilia A when he marries Hill, who does not have the disorder. Jane's parents also do not have hemophilia, but her brother Steve Hill does. What is the probability that the Marlows' son will have the disorder? What is the probability that their daughter will have hemophilia? Are there chances that their daughter will be a carrier of this disorder?

Purchase this Solution
Solution Summary

This solution discusses the transmission of X-linked diseases by providing external information sources as well as a PowerPoint presentation with diagrammatic explanations.

Solution Preview

1. Genetic testing can detect Duchenne Muscular Dystrophy (DMD) if a known mutation is present. Prenatal genetic testing has increased the rate of DMD detection. The following article, http://www.nature.com/ejhg/journal/v21/n1/full/ejhg2012101a.html, discusses the lack of DNA testing for female fetuses. However, due to their possible carrier ability, the author felt this policy needs to change. Another option for DMD detection is neonatal testing. This is also discussed in the ...

Purchase this Solution
Free BrainMass Quizzes
First Aid

Do you know how to provide first aid?

Labor and Delivery

Do you know about the stages of delivery? Find out with this quiz!

Test your health planning and program evaluation knowledge

Health planning and program evaluation is an important aspect of the Health Sciences' field. Organizations and communities must understand the needs of their audiences, and a way to obtain this datum is through proper design and assessment. This quiz will test your ability to understand the importance of planning and evaluation in the health sector.

Managed Care Organizations

This quiz will test the basics of managed care organizations. It is important to know how our health care delivery system operates through managed care.

Crohn's Disease

How much do you know about this condition?

View More Free Quizzes
Related BrainMass Solutions

  • Mechanisms of Evolution and the Theory of Natural Selection

    Biodiversity is crucial to continued evolution because the more variations there are for a given species the more random genetic events occur (genetic drift; one of the mechanisms of evolution) and over time given very specific selective forces the fittest

  • What is the histone code?

    Allis, Science 293, 1074 (2001) This solution provides a description of the parts of histones involved, their variations, and their general purpose within the genetic code.

  • The relationship between biodiversity and evolution

    183997 How biodiversity and evolution are related According to the theory of natural selection, variations in populations provide the raw material for evolution. Describe how the following variations allow for natural selection. A.

  • Mechanisms of evolution, natural selection, mutation

    that do not possess these variations.

  • Genetic Diversity of Crop Plants & Livestock

    254146 Genetic Diversity Define genetic diversity and explain the importance of genetic diversity for crop plants and livestock Genetic diversity refers to any variation in the nucleotides, genes, chromosomes, or whole genomes of organisms.

  • Mechanisms of evolution

    In other words the offspring that has 'fittest' genetic make up (these variations happen at random) have the best chance of survival given very specific conditions. For example, consider different types of Angiosperms (a huge family of plants).

  • Attention Deficit Hyperactivity Disorder and Genes

    Variations in genes that regulate specific dopamine receptors have been identified in a high proportion of people with addictions and ADHD.

  • Genetic variation

    How did Darwin relate the natural variations found within species to the organisms that tend to live longer and reproduce more often? 1. The high incidence of dwarfism among old order Amish is due to extensive inbreeding.

  • Characteristics of DNA and RNA molecules and their function:

    DNA is capable of undergoing mutation and recombination which bring about variations, which in turn play an important role in speciation. Hence variations are regarded as food for evolution.

  • Variation in Alcohol dehydrogenase (ADH)

    VARIATION IN ALCOHOL METABOLISM AMONG INDIVIDUALS OF DIFFERENT POPULATION: Genetic Variations in ADH and ALDH can explain why different individuals react differently to alcohol.

View More Related Solutions