Predict the most likekly mononitration product from each of the following compounds. Explain the reasons.
b) 4-ethyl toluene
d) Br-C6H4-COOCH2CH3 (1bromobenze 3-ethyl acetate)
There are a number of substituents to consider here:
fluoro, methyl, ethyl, nitro, bromo, ester.
They can be classed into groups, accoridng to their directing effect on nitration:
Halo- groups direct nitration to positions 4, 2 and 3 (in that order) and tend to deactivate the nitration process.
Alkyl groups also direct nitration to positions 4, 2 and then 3 but this is because they activate the nitration process.
Ester and nitro groups direct to 3 and then 2 and 4 by deactivating.
This last group is ...
The solution contains guidance on how to go about predicting the most likely mononitration products from a series of specified compounds including benzotriflouride, 1,3-dimethyl-5-nitrobenzene and others.