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1) Define a genetic mutation and state the types of genetic mutations. Discuss the effects of genetic mutations.

2) A thirteen-year-old girl, who is underdeveloped and thin, has a blood disorder. She frequently experiences chest and abdominal pain, fever, and coughing, and has trouble breathing. Her teachers often spend additional time with her, explaining concepts that the rest of the class is familiar with, as she tires very easily and is able to concentrate only for short spans of time.

Identify the blood disorder that she might be suffering from.

Describe in detail the symptoms of this blood disorder.

Explain the difference in the cells of this girl and a person who does not suffer from the disorder.

Any help would be greatly appreciated..

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A genetic mutation is a change occurring at the genetic material of an organism. The usual causes of genetic mutation in humans are their exposure to radiation, chemicals, viruses, and other mutagens.

The types of genetic mutation are as follows:
- frameshift mutation
- missense ...

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Gene Mutation

Give a brief description of each of the following:
a.heritable mutation
b.nutritional mutation
c.conditional mutation
a.Write a wild-type DNA sequence with 10 bases and under it write the sequence after a transversion and a transition has occurred. Underline and label both mutations.
b.Write a DNA sequence of 10 bases, and show how a missense mutation results in a mutant sequence. Show the sequence of the transcript and hypothetical amino acid sequence.
c.Repeat part b., but this time show the consequences of a frameshift mutation?
a.Give an example of a spontaneous mutation.
b.Describe what type of mutation results from exposure to UV light.
c.When DNA in a cell undergoes a UV radiation-induced mutation, what are the two possible options for this cell?
Describe an experiment you would do to determine if a food preservative was a mutagen.
a.In a suburb of New York, out of 135,000 people, 64 had a dominant genetic disease; 4 of these individuals had an affected parent. What is the mutation rate for this gene?
b.What does this value mean?

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