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How HIV Infects Helper T Cells

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This solution will review the basics of viruses and discuss the process that occurs when a helper T cell is infected by the HIV virus. It includes a glossary to aid in understanding of the technical terms, that occur in a first year introductory college biology class.

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First, let me review the basics about viruses. Viruses are merely a piece of RNA or DNA, depending upon the type of virus, that is surrounded by a protein coat. They have a very small genome and cannot replicate this genetic material on their own. They cannot reproduce outside of a host cell, therefore they are not considered a living thing.

1.The HIV virus enters a helper T cell and attaches to a specific receptor located on the surface of the T cell membrane, CD4 + fusin. It works much like enzymes do because the CD4 receptor is a certain shape. When this happens the virus and the cell membrane fuse and the core of the virus enters the cell.

2. At this point, the viral RNA and the core proteins are ...

Solution Summary

This solution reviews the basics of viruses and discuss the 4-step process that occurs when a helper T cell is infected by the HIV virus. The posting totals 517 words with 1 reference and a 5-word glossary of the technical terms.

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Pathogenicity and Immunology; Host resistance and the immune (CASE4)

In this module you have learned of the importance of the immune system in protecting against disease. For the Module 4 case assignment you will investigate the virus HIV and its effect on the human immune system, as well as important topics in infectious disease in general.

It is estimated that over 34 million people globally are living with HIV/AIDS. (http://www.avert.org) Acqiured immune deficiency syndrome (AIDS) has been described as the most common secondary immune deficiency disease in the world. Infection with the human immune deficiency virus (HIV) has been identified as the cause of AIDS. For the module 4 case assignment prepare a paper addressing the following:

Provide a general discussion of HIV/AIDS. In your paper discuss the structure of HIV and how the viral structure facilitates entry into host cells. Begin your research in your Introductory Microbiology textbook, using "Ch 11: Microbial Epidemiology," Ch 7: Viral Effects on Cells," and "Ch 17: Viruses and Prions" in A Concise Manual of Pathogenic Microbiology.

Discuss the function of HIV protease, integrase, and reverse transcriptase.
Explain how this pathogen causes disease in the host.
Identify the characteristics of HIV which account for its transmission. Include the basic epidemiology of this virus and its method of transfer.
The normal function of the immune system. Be sure to explain the function of B-lymphocytes, killer T-lymphocytes, helper T-lymphocytes, and macrophages.
The function of the complement system.
How HIV alters normal function of the immune system.
Note: The assignment will require you to engage in independent research. Begin by reading through the chapters listed above.

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