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summarizing a scientific article on cell biology

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I need help paraphrasing the attached article entitled, "Depletion of E-Cadherin Disrupts Establishment but Not Maintenance of Cell Junctions in MDCK Epithelial Cells."

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https://brainmass.com/biology/research-methods-and-experimental-design/summarizing-scientific-article-cell-biology-187888

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The authors used Madin-Darby canine kidney cells as a model to test the importance of E-cadherin and a-catenin in the formation and maintenance of epithelial intercellular tight junctions. What they found suggests that E-cadherin and Cadherin-6 act as scaffolding during the construction of polarized structures in the junction, however they are largely dispensable in mature junctions. On the other hand, a-catenin is essential for the maintenance of functioning ...

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In this solution I help the student to summarize a peer-reviewed journal article related to E-cadherin and epithelial cell junctions.

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1. Introduction/background information about the species - Include common and scientific names of the organism, the area you and this species live (country, state, city, etc.), the area's biome classification, etc.

2. Life cycle of the species- Describe the life cycle of the organism you have chosen. The life cycle of an organism refers to the series of changes in both development and growth from its beginnings as an independent life form up until maturity, when it is able to reproduce. Organisms like bacteria have relatively simple life cycles; however other organisms (e.g., plants) have very complex stages to their life cycle.

3. Structure and Function- Describe the structure and function of at least one major organ system of the species (e.g., digestive system, reproductive system). Choose one system and explain how this organism's system is structured anatomically and physiologically. Identify any species-specific characteristics or adaptations that are particularly unique to this organism and explain why.

4. Evolution of the organism - Evolution is simply heritable change over time. Sometimes changes from one generation to the next can give individuals an advantage. Specifically a trait that increases reproductive success or survival ability could be advantageous. Include a section in your profile paper about your organism's evolution. Here are possible ways to research the topic:

a. Conduct a review of scientific literature to understand what is known about your organism's past evolution. Search key words may include evolution, fossil, ancestor. Often technical reports from wildlife and conservation agencies have descriptions of an organism's evolution.

b. Summarize research on any adaptive traits. Search key words include adaptation, evolution, trait, and character.

c. Find an article on the family tree or phylogeny of your organism. Summarize the information describing related species. Search key words might include phylogeny, phylogenetic, and genetic analysis.

d. Use the Tree of Life Project to describe the phylogeny of your organism. Start at species, if possible, and trace back to the root. In addition to your summary, include any interesting patterns or unknown data.

5. Additional interests - The diversity of biological organisms is vast. Therefore, if your organism has a particularly interesting aspect about its biology that is not covered in the life cycle, structure and function, and evolution add a section to your paper on that aspect. For example, if your species has an interesting parental care strategy or mating system (i.e., protrandry/protogyny, polygymy, promiscuity, monogamy) you can include that in your paper.

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