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Tumor Antigens

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Please explain the difference between a tumor antigen and a tumor marker.
What are the two categories of tumor antigens?
How are tumor markers used in diagnosis?

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Solution Summary

This solution compares and contrasts tumor markers and tumor antigens and provides and introductory overview of these two substances related to cancer. Additionally, the solution includes four reference sources for further investigation of the subject.

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There is a difference between a tumor antigen and a tumor marker. A tumor antigen is an antigenic substance produced in tumor cells that triggers an immune response in the host. Tumor markers are substances that are produced by cancer cells or by other cells of the body in response to cancer or certain benign (noncancerous) conditions. They can be produced directly by the tumor or by non-tumor cells as a response to the presence of a tumor. Most tumor markers are tumor antigens, but not all tumor antigens can be used as tumor markers.

Tumor antigens are loosely classified into two ...

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