Enzymes expressed by bacteria that serve as virulence factors
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Using specific examples, outline how virulence factor enzymes aid in the development of pathogenic infections.
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Solution Summary
Virulence factors are molecules expressed and secreted by bacteria that enable them to achieve the following:
• colonization of a niche in the host (this includes adhesion to cells) for example, Trimeric Autotransporter Adhesins (TAA)
• immunoevasion, evasion of the host's immune response
• immunosuppression, inhibition of the host's immune response
• entry into and exit out of cells (if the pathogen is an intracellular one)
• obtain nutrition from the host."
Specifically, this answer addresses enzymes used by bacteria as virulence factors and gives,examples: Group A Strep, Salmonella species, Neisseria gonorrhoeae, and Helicobacter pylori.
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Using specific examples, outline how virulence factor enzymes aid in the development of pathogenic infections.
Straight from Wiki, virulence factors are "molecules expressed and secreted by pathogens (bacteria, viruses, fungi and protozoa) that enable them to achieve the following:
• colonization of a niche in the host (this includes adhesion to cells) for example, Trimeric Autotransporter Adhesins (TAA)
• immunoevasion, evasion of the host's immune response
• immunosuppression, inhibition of the host's immune response
• entry into and exit out of cells (if the pathogen is an intracellular one)
• obtain nutrition from the host."
http://en.wikipedia.org/wiki/Virulence_factors
I will touch on a few of these.
I. Group A Strep (Streptococcus pyogenes)
The cell wall of S pyogenes is very complex and chemically diverse. The antigenic components of the cell are the virulence ...
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