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Lactic Acid Production

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A new drug was found to decrease Hepatitis B virus. The drug is an analogue of one of the nucleic acid bases of DNA and probably works by being incorporated into the virus and disrupting viral genes during viral DNA replication. However, patients in a clinical trial of the drug began to experience drastic overproduction of lactic acid and liver failure leading to death. What is the most likely explanation for the problem? Why did fermentation occur?

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1. A new drug was found to decrease Hepatitis B virus. The drug is an analogue of one of the nucleic acid bases of DNA and probably works by being incorporated into the virus and disrupting viral genes during viral DNA replication. However, patients in a clinical trial of the drug began to experience drastic overproduction of lactic acid and liver failure ...

Solution Summary

This solution explains the most likely explanation for the reaction of a new drug for Hepatitis B, an analogue of one of the nucleic acid bases of DNA, in a clinical trial of the drug, and why fermentation might have occurred.

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