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    Mutation Characteristics of the Gene that Codes for CAK

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    Of the genes that code for CAK, wee1, and cdc25, which would you expect, when mutated, to stop a cell from continuing to divide? Which would you expect, when mutated, to cause the cell to proliferate in an uncontrolled manner?

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    CAK, wee1 and cdc25 are all involved in cell cycle control through the modulation of cyclin-dependent kinase (Cdk) activity.

    The Cdk-cyclin complex acts at the G2/M cell checkpoint to activate mitosis, once certain critical conditions such as cell size have been met. It can be inhibited by CDK phosphorylation at T14 and Y15, and requires Cdk phosphorylation at T161 in order to function.

    The three genes listed above have the following ...

    Solution Summary

    The expert examines mutation characteristics of the Gene that Codes for CAK.