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Calculation of dominant and recessive alleles in population

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1. Imagine a population of 10,000 humans living on an isolated island. Every generation, an average of one individual is born with cystic fibrosis, a fatal genetic disease caused by a recessive allele (ie., individuals with the condition are cc, Cc individuals are unaffected, but carry the allele)

What are the frequencies of the dominant, and recessive alleles?

What proportion of the population are carriers?

What is the selection coefficient against individuals with the disease?

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Solution Summary

Dominant and recessive alleles in a population can be calculated by using Hardyweinberg Law. Based on availability of simple data like population size and frequency of recessive alleles, allelic distribution can be calculated.

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1. Imagine a population of 10,000 humans living on an isolated island. Every generation, an average of one individual is born with cystic fibrosis, a fatal genetic disease caused by a recessive allele (ie., individuals with the condition are cc, Cc individuals are unaffected, but carry the allele)
What are the frequencies of the dominant, and recessive alleles?
What proportion of the population are carriers?
What is ...

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