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Cell Adhesion and Cadherins

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How do cadherins plays an important role in cell to cell junctions? How do experimental techniques prove it, and what they conclude?

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Tissues are composed of cells that are held together by a variety of cell to cell junctions created by transmembrane and extracellular proteins and ions. These junctions include: adherence junctions, tight junctions and gap junctions. Adherence junctions are composed of transmembrane proteins cadherin. These proteins require calcium to facilitate their interactions. Certain cadherins are tissue specific ...

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Two paragraphs with web references as to the role of cadherins in cell to cell adhesion and their function in the organism as a whole.

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