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The pre-B cell receptor

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I describe the pre-B cell receptor (preBCR) and the expression of its component parts during B cell development. I further discuss its possible functional roles in precursor B cell differentiation, proliferation and selection.

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The pre-B cell receptor is explained. The receptors and components which are featured in the topics are given.

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The pre-B cell receptor is only expressed transiently and it is an important check point in B cell development. The pre-B cell receptor signals to the cell that a complete ...

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