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    Reaction process for Lactate Dehydrogenase catayzed

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    Lactate dehydrogenase catalyzes the reversible reaction:

    Pyruvate + NADH + H^(+) --> Lactate + NAD^(+)

    Given the following facts, (a) tell in which direction the reaction will tend to go if NAD^(+), NADH, pyruvate, and lactate were mixed, all at 1 M concentrations, in the presence of lactate dehydrogenase at pH 7; (b) calculate ΔG'° for this reaction; (c) calculate Keq' for this reaction.

    NAD^(+) + H^(+) + 2e- --> NADH E'° = -0.32 V
    pyruvate + 2H^(+) + 2e- --> lactate E'° = -0.19 V

    The Faraday constant, F, is 96.48 kJ/V?mol.

    © BrainMass Inc. brainmass.com October 9, 2019, 8:09 pm ad1c9bdddf
    https://brainmass.com/biology/biological-chemistry/reaction-process-lactate-dehydrogenase-catalyzed-141407

    Solution Preview

    Lactate dehydrogenase catalyzes the reversible reaction:

    Pyruvate + NADH + H+ --> Lactate + NAD+

    Given the following facts, (a) tell in which direction the reaction will tend to go if NAD^(+), NADH, pyruvate, and lactate were mixed, all at 1 M concentrations, in the presence of lactate dehydrogenase at pH 7; (b) calculate ΔG'° for this reaction; (c) calculate Keq' for this reaction.

    NAD+ + H+ + 2e- --> NADH E'° = -0.32 V
    pyruvate + 2H+ + 2e- --> lactate E'° = -0.19 V

    The Faraday constant, F, is ...

    Solution Summary

    The solution determines which direction the reaction will send to go. It also calculates the ΔG'° and Keq' for this reaction.

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