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    Hydrolysis of Phosphocreatine

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    For the hydrolysis of phosphocreatine:
    Phosphocreatine + H2O==creatine + Pi
    the standard state deltaG is -42.8 kJ/mol at 37 degrees celsius. If in a given cell the concentration of creatine is 1.7mM, phosphate is 5.8mM, and phosphocreatine is 6.4mM, what is the deltaG for hydrolysis of phosphocreatine in the cell? Nearest 0.1kJ/mol.

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    Solution Preview

    In the reaction,

    A + B <-----> C + D

    the following is true,

    &#916;G = &#916;G°' + RT ln([C][D]/[A][B])

    Therefore, in this reaction,

    Phosphocreatine + H2O <------> creatine + Pi

    the following is true,

    &#916;G = &#916;G°' + RT ...

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