Hydrolysis of Phosphocreatine
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For the hydrolysis of phosphocreatine:
Phosphocreatine + H2O==creatine + Pi
the standard state deltaG is -42.8 kJ/mol at 37 degrees celsius. If in a given cell the concentration of creatine is 1.7mM, phosphate is 5.8mM, and phosphocreatine is 6.4mM, what is the deltaG for hydrolysis of phosphocreatine in the cell? Nearest 0.1kJ/mol.
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In the reaction,
A + B <-----> C + D
the following is true,
ΔG = ΔG°' + RT ln([C][D]/[A][B])
Therefore, in this reaction,
Phosphocreatine + H2O <------> creatine + Pi
the following is true,
ΔG = ΔG°' + RT ...
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