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    What if the activity of phosphodiesterase was blocked ?

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    If the activity of phosphodiesterase was blocked, how would a cell be affected if it normally responded to hormonal stimulation through a second messenger system? Be specific.

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    Solution Preview

    For a second messenger to work effectively it must have the following characteristics:

    Amplification - when a few hormone molecules signal the cell, it needs to respond with a signal that is strong enough to get a job done without repeated high levels of stimulation.

    Control --- eventually a response must be shut down .

    Specificity - when a hormone is released, a given cell should respond in a specific way.
    Role of phosphodiesterase is in ...

    Solution Summary

    Explanation of the second messenger system in more than 250 words is provided in the solution.