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# Husband and wife are both sickle cell carriers.

Give a precise, complete and unambiguous response to this question, free of mathematical jargon to the following question. Please consider issues as the independence of events or the relative frequency definition of probability.

Husband and wife are both sickle cell carriers. The doctor says that the husband and wife should expect that 1 in 4 children to have sickle cell disease. Husband and wife have already had 3 healthy children. The couple wish to have a 4th child. The couple believe that the doctor's remarks indicate that the next child is certain to have sickle cell disease.

#### Solution Preview

As the problem does not indicate the particular objective, I'm assuming the objective here is to determine whether it is certain for the 4th child to have sickle cell disease.

First of all, I'd like to distinguish between probability and relative frequency. Probability is what you will find ...

#### Solution Summary

The solution provides a detailed and step-by-step explanation for the problem.

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