Treating Chronic Fatigue Syndrome Patients with chronic fatigue syndrome were tested, then retested after being treated with fluorocortisone. Listed below are the changes in fatigue after the treatment (based on data from "The Relationship Between Neurally Mediated Hypertension and the Chronic Fatigue Syndrome" by Boi Holaigah, Rowe, Kan, and Calkins, Journal of the American Medical Association Vol. 274, No. 12). A standard scale from -7 to +7 was used, with positive values rep resenting improvements. Use a 0.01 significance level to test the claim that the mean change is positive. Does the treatment appear to be effective?
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The solution provides step by step method for the calculation of Z test . Formula for the calculation and Interpretations of the results are also included.