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    Hypothesis Testing of Mean: Chronic Fatigue Syndrome

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    Patients with Chronic Fatigue Syndrome were tested, and then retested after being treated with fludrocortisone. The changes in fatigue after treatment were measured (based on data from "The Relationship between Neurally Mediated Hypotension and the Chronic Fatigue Syndrome" by Bou-Holaigah, Rowe, Kan, and Calkins, Journal of the American Medical Association, Vol.274, No. 12). A standard scale from -7 to +7 was used with positive values representing improvements. The sample of 21 patients had a mean score of 4 on the scale with a sample standard deviation, s = 2.17 Use a 1% level of significance level to test the hypothesis that the mean change is positive(i.e. there is improvement.). Does the treatment appear to be effective?

    State the Null Hypothesis and the Alternative Hypothesis.

    Determine the test statistic.

    Determine the P-value.

    Make a decision regarding the hypotheses based on the P-value and the Level of Significance.

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    Solution Summary

    The solution provides step by step method for the calculation of testing of hypothesis. Formula for the calculation and Interpretations of the results are also included. Interactive excel sheet is included. The user can edit the inputs and obtain the complete results for a new set of data.