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    GABA and Benzodiazepines: The Mechanism of Action

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    Benzodiazepines Their mechanism of action: They are "allosteric modulators of the GABA-A chloride ionophore. I dont understand what "allosteric modulators of the GABA-A chloride ionophore means? Any thoughts or comments welcome

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    "allosteric modulators of the GABA-A chloride ionophore":

    i)GABA binds to receptors and ion channel opens
    ii) Benzodiazepine molecules bind to receptors and enhance opening of chloride ion ...

    Solution Summary

    Discussion of Benzos actions on GABA receptors and it actions on the chloride ions channels.