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GABA and Benzodiazepines: The Mechanism of Action

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Benzodiazepines Their mechanism of action: They are "allosteric modulators of the GABA-A chloride ionophore. I dont understand what "allosteric modulators of the GABA-A chloride ionophore means? Any thoughts or comments welcome

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Solution Summary

Discussion of Benzos actions on GABA receptors and it actions on the chloride ions channels.

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"allosteric modulators of the GABA-A chloride ionophore":

i)GABA binds to receptors and ion channel opens
ii) Benzodiazepine molecules bind to receptors and enhance opening of chloride ion ...

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