Benzodiazepines Their mechanism of action: They are "allosteric modulators of the GABA-A chloride ionophore. I dont understand what "allosteric modulators of the GABA-A chloride ionophore means? Any thoughts or comments welcome© BrainMass Inc. brainmass.com October 10, 2019, 7:31 am ad1c9bdddf
"allosteric modulators of the GABA-A chloride ionophore":
i)GABA binds to receptors and ion channel opens
ii) Benzodiazepine molecules bind to receptors and enhance opening of chloride ion ...
Discussion of Benzos actions on GABA receptors and it actions on the chloride ions channels.