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neuropathology of Autism and Williams Syndrome

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Compare and contrast the neuropathology of Autism and Williams Syndrome.

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The neuropathology of Autism and Williams Syndrome are compared.

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A major neuropathological contrast between Williams syndrome (WS) and autism is found in the cerebellum - a part of the brain.

Williams syndrome is caused by a microdeletion on chromosome 7q11.23, which causes cognitive impairment and a variety of physical abnormalities. Brain abnormalities, including decreased brain size, with a relatively greater decrease in the volume of the cerebral white matter volume as compared to the cerebral gray matter. WS patients have greater ratio of frontal to posterior regional volume; also ...

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