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    Organic Chemistry Questions on Nucleophilic Substitution

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    Questions:
    1. In the purification process, the organic layer is washed sequentially with 2 M NaOH, water, and saturated aqueous sodium chloride. What is the purpose of each of these washes and why is cold 2 M NaOH recommended?
    2. How would doubling the concentration of the nucleophile affect the rate of an SN2 reaction?
    3. Specify the most electrophilic carbon atom in 1-butanol and rationalize your choice.

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    Solution Preview

    1. NaOH is used usually to remove any acid formed. HBr could form which will then be neutralized by NaOH. Cold solutions are ...

    Solution Summary

    This solution helps with a problem regarding organic chemistry.

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