Nitration of anisole- electrophilic aromatic substitution
Not what you're looking for?
Describe with anisole as an example what are the major products obtained as a result of nitration of with HNO3+H2SO4. Also indicate the resonace structures for each mechanism involved inculding the formation of nitronium ion.
Purchase this Solution
Solution Summary
Attachment of an electrophile ortho or para to them leads to a more stable complex because of resonance involving the electrondonating substituent. On the other hand, meta attack does not permit any resonance stabilization or interaction and order of the distribution of final products in the reaction is Para>ortho>>meta (kp>ko>>km).
Solution Preview
By using sulfuric acid with nitric acid to form the nitronium ion electrophile
NO2+ then forms a sigma complex with benzene or substituted benzene (here anisole), and loses H+ to form nitrocompound
--Remember that alkyl groups stabilize the sigma complex by induction, donating electron density through the sigma bond.
--Substituents with a lone pair of electrons like -OCH3 stabilize the sigma complex by resonance.
Attachment of an electrophile ortho or para to them leads to a more stable complex because of ...
Purchase this Solution
Free BrainMass Quizzes
Functional groups in Organic Chemistry
You will be tested on the names of functional groups in Organic Chemistry. It is very important to know the functional groups to understand Organic reactions.
Match Elements with their Symbols
Elements are provided: choose the matching one- or two-letter symbol for each element.
Organic Chemistry Naming: Alkanes
This is a quiz which is designed to assist students with learning the nomenclature used to identify organic compounds. This quiz focuses on the organic compounds called Alkanes.
General Chemistry - Classification of Matter
This test will assess your knowledge on the classification of matter which includes elements, compounds and mixtures.