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Hydrolysis

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When the alkyl bromides (shown below) were subjected to hydrolysis in a mixture of ethanol and water (80% CH3CH2OH/20% H2O) at 55OC, the rates of the reaction showed the following order:

(CH3)3CBr > CH3Br > CH3CH2Br > (CH3)2CHBr

Provide an explanation for this order of reactivity.

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Solution Summary

Provides steps necessary to determine the order of reactivity in 130 words.

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This is a SN2 reaction We have inversion of configuration with OH substituting the Br leaving group on the backside of the carbon center.

Most likely we are looking at a competition between SN1 ...

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