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How conditions alter rate of enzyme-catalyzed reaction

How will each of the following changes in condition alter the rate of an enzyme-catalyzed reaction:

-decreasing temp to 10 deg C?

-increasing the pH of the solution from 7 to 11?

-heating only the enzyme to 100 deg C?

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1. From 0 to about 40-50o C, enzyme activity usually increases. Conversely, a temperature of 10 degree C is not optimal for reaction ...