Purchase Solution

stabilization of DNA strand by histones

Not what you're looking for?

Ask Custom Question

The typical length of a DNA strand is 3.4cm. In order to fit into a cell, the DNA strand is supercoiled around proteins called histones. Histones are a family of five proteins thet are rich in the amino acids and lysine. How do histones stabilize the DNA strand? (look at the backbone of the DNA strand at the molecular level.)

Does a mutation causing a substitution of one base pair in a strand of DNA necessarily result in a new amino acid in the protein coded for that gene? Explain.

Purchase this Solution
Solution Summary

It explains how histones stabilize the DNA strand. It also explains the mutation in DNA.

Solution Preview

Hi

The deoxyribose sugar-phosphate backbone of the DNA molecule is negatively charged due to all of the phosphate groups. Histones are basic proteins (as opposed to acidic proteins) with lots of positive charges due to a high proportion ...

Purchase this Solution
Free BrainMass Quizzes
Periodic table

Match Elements with their Symbols

Elements are provided: choose the matching one- or two-letter symbol for each element.

General Chemistry - Classification of Matter

This test will assess your knowledge on the classification of matter which includes elements, compounds and mixtures.

Thermochemistry

The quiz helps in revising basic concepts about thermochemistry.

Organic Chemistry Naming: Alkanes

This is a quiz which is designed to assist students with learning the nomenclature used to identify organic compounds. This quiz focuses on the organic compounds called Alkanes.

View More Free Quizzes
Related BrainMass Solutions

  • cell genetics and genetic information

    of DNA a) Which strand of DNA is transcribed and in which direction?

  • Transcription in Eukaryotes

    An R-loop is a single stranded loop section of DNA (ssDNA) formed by the association of a section of ssRNA (single stranded RNA) with a strand of t DNA whereby one DNA strand that would be part of a dsDNA (double stranded DNA) complex is displaced as

  • DNA: History, Discovery, Structure, Replication, and Application

    DNA is tightly packaged into chromosomes. DNA is packed around protein molecules known as "Histones" in a chromosome. Humans have 23 pairs of chromosome in every cell. So total we have 46 chromosomes.

  • Chromatin and DNA modifications vs RNA

    regulation of gene expression mediated by the histone and DNA modifications and that controlled by the RNAi pathway is that the first type of regulation acts at the level of the DNA transcription, while the second type of regulation targets the mRNA

  • Molecular and Cell Biology

    Another method requires the two broken strands of DNA to resect part of one strand of DNA, creating a long single-stranded overhang.

  • What is the histone code?

    88582 The Histone Code What is meant by the "histone code"? Describe the parts of histones involved, their variations, and their general purpose. The histone code creates a means of regulating transcription beyond that created by the genetic codes.

  • DNA Sequence Variation, Epigenetics, and Gel Electrophoresis

    Basically, we can make modifications to the histones (primarily by acetylation and deacetylation) that help wrap DNA into chromosomes or to the DNA itself (methylation and demethylation, primarily).

  • DNA Synthesis

    As each deoxyribonucleoside triphosphate join the new DNA strand by reacting with the 3'-hydroxyl end of the growing DNA strand, it loses two phosphate groups (PPi). (1) The hydrolysis of the triphosphate group on the deoxyribonucleoside triphosphate

  • Complimentary base paring in DNA

    It is enzyme driven process consisting of following steps : 1. Unwinding of DNA chain by enzyme helicase 2. Priming by Primase in which small segment of RNA is formed on the DNA strand 3.

View More Related Solutions