Explore BrainMass

Explore BrainMass

    Using Acid Chlorides to Prepare Aromatic Ketones

    Not what you're looking for? Search our solutions OR ask your own Custom question.

    This content was COPIED from BrainMass.com - View the original, and get the already-completed solution here!

    Acid chlorides are used as electrophiles in the Friedel-Crafts reaction to prepare aromatic ketones. The reaction involves the transfer of an aromatic hydrocarbon with an acyl chloride in the presence of a lewis acid, such as AlCl3. Using this reaction, outline the reaction sequence you would use to prepare:
    a) ethyl phenyl ketone
    b) benzophenone

    © BrainMass Inc. brainmass.com December 24, 2021, 5:00 pm ad1c9bdddf

    Solution Preview

    First reaction: preparation of ethyl-phenyl ketone

    See attached file for the reaction equation.

    How it is done:
    Propanoyl chloride is added carefully to a mixture of benzene and solid aluminium chloride in the cold. Hydrogen chloride gas is given off.

    When all the propanoyl chloride has ...

    Solution Summary

    The preparation of ethyl-phenyl ketone and benzophenone is explained. Reaction equations are included in two attached PDF files.