Using Acid Chlorides to Prepare Aromatic Ketones
Acid chlorides are used as electrophiles in the Friedel-Crafts reaction to prepare aromatic ketones. The reaction involves the transfer of an aromatic hydrocarbon with an acyl chloride in the presence of a lewis acid, such as AlCl3. Using this reaction, outline the reaction sequence you would use to prepare:
a) ethyl phenyl ketone
b) benzophenone
https://brainmass.com/chemistry/acid-and-base-organic-chemistry/using-acid-chlorides-prepare-aromatic-ketones-21663
Solution Preview
First reaction: preparation of ethyl-phenyl ketone
See attached file for the reaction equation.
How it is done:
Propanoyl chloride is added carefully to a mixture of benzene and solid aluminium chloride in the cold. Hydrogen chloride gas is given off.
When all the propanoyl chloride has ...
Solution Summary
The preparation of ethyl-phenyl ketone and benzophenone is explained. Reaction equations are included in two attached PDF files.