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    Autoimmunity and Tolerance

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    In a multiple-choice quiz the question was: The lack of an immune response to self is called:

    A. Autoimmunity
    B. Tolerance

    The answer was B. Can you explain why tolerance is the best answer? Thanks.

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    https://brainmass.com/biology/pathology/autoimmunity-and-tolerance-13677

    Solution Preview

    The lack of an immune response to self is called:

    A.
    B. Tolerance

    The correct answer is B.

    This is tricky, but it is a matter of definition. Tolerance is the lack of an immune response to self. MHC molecules (gene products from MHC genes) control the body's ability to recognize self and non-self. When T cells mature in the thymus, they are checked for their reactivity ...

    Solution Summary

    This solution explains the difference between autoimmunity and tolerance, and further delineates why tolerance is referred to the lack of an immune response to self.

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