Explore BrainMass

Growth Hormone Signaling

This content was STOLEN from BrainMass.com - View the original, and get the already-completed solution here!

Human growth hormone binds to a cell surface membrane protein that is not a receptor tyrosine kinase. The intracellular domain of the receptor can bind other proteins inside the cell. Furthermore, studies indicate that the receptor is monomeric in the absence of hormone but dimerizes on hormone binding. Propose a possible mechanism for growth hormone signaling.

© BrainMass Inc. brainmass.com December 19, 2018, 11:37 pm ad1c9bdddf

Solution Preview

Receptor dimerization is a common mechanism used in signaling cascades. The presentation of the ligand binds to the cell ...

Solution Summary

Short paragraph and reference examining the importance of receptor dimerization in growth hormon signaling.