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    Antibiotic classes are reviewed

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    List of common antibiotic classes, mechanism of action, and examples. This is best used to review for a test. This is a Word document (.doc).

    © BrainMass Inc. brainmass.com October 3, 2022, 10:50 pm ad1c9bdddf
    https://brainmass.com/biology/human-biology/antibiotic-classes-reviewed-325671

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    Antibiotic classes
    Macrolide
    • Mechanism of Action (MOA): binds to P site of 50S ribosomal subunit, interfering w/ protein synthesis
    • Effective against: Gram negative rods, anaerobic bacteria, Gram positive rods, acid-fast rods, micoplasmas
    • Examples: Clarithromycin, Erythromycin
    Azalide
    • MOA: bacteriostatic; binds to P site of 50S ribosomal subunit, interfering w/protein synthesis
    • Effective against: Gram negative rods, chlamydiae
    • Example: Azithromycin
    Extended spectrum cephalosporin (3rd generation)
    • MOA: Bactericidal; inhibits cell wall mucopeptide synthesis
    • Effective against: gram negative rods (E. coli)
    • Examples: Ceftriaxone, Ceftazidime, Cefepime
    Fluoroquinolone
    • MOA: bactericidal; inhibits DNA gyrase and topoisomerase IV
    • Effective against: gram negative cocci, gram negative rods, Gram positive rods
    • Examples: Gatifloxacin, Levofloxacin, Ciprofloxacin
    Aminoglycosides
    • MOA: bactericidal; binds to bacterial 30S ribosomal subunit, inhibiting protein synthesis
    • Effective against: acid-fast rods
    • Examples: Gentamicin, Tobramycin
    Tetracyclines
    • MOA: bacteriostatic; inhibits protein synthesis
    • Effective against: Gram positive rods, chlamydiae, rickettsiae
    • Examples: Tetracycline, Doxycycline, Minocycline
    Penicillins
    • MOA: bactericidal; inhibits cell wall mucopeptide synthesis
    • Effective against: Gram positive cocci, Gram positive rods, spirochetes
    • Examples: Penicillin, Amoxicillin, Augmentin
    Sulfonamides
    • MOA: bacteriostatic; inhibits dihydropteroate synthetase
    • Example: Sulfadiazine

    This content was COPIED from BrainMass.com - View the original, and get the already-completed solution here!

    © BrainMass Inc. brainmass.com October 3, 2022, 10:50 pm ad1c9bdddf>
    https://brainmass.com/biology/human-biology/antibiotic-classes-reviewed-325671

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