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    Transcription in eukaryotes

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    Compared to prokaryotes, the eukaryotic genome is more complex and contains large amounts of noncoding sequences. Describe the process by which eukaryotic promoters are recognized. How does the transcriptional machinery find the appropriate promoters in the complex eukaryotic nucleus?

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    The core promoter DNA elements bind and control preinitiation complex assembly containing Pol II, transcription factor and coactivators. They position the transcription start site and control transcriptional directionality and they respond to activators and repressors in their vicinity in a cell. The preinitiation complex contains two classes of factors. ...

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    This solution explains transcription in eukaryotes.