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Difficulties Encountered in Gene Therapy

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What are the difficulties encountered by gene therapy procedures?

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This solution outlines some of the difficulties associated with gene therapy procedures.

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It is very hard to introduce new genes into preexisting, differentiated cells. Generally, gene therapy will only be successful if the gene can be introduced into millions of cells all within a single tissue. And, of course, the target must be specific. That means, the specific cells within the specific tissue. Thus, targeting is a major obstacle and challenge. If the wrong tissue gets targeted or even the germline, ...

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