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Hender/Hasselbach and E-amino Groups

The E-amino group of lysine has a pka of 10.5:
a) What fraction of these groups will be protonated in a dilute solution of lysine at pH 9.5?
b) At pH 11.0?

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Solution Preview

Please refer to the attached file. Cheers.

Here, the protonated form (acidic form) of lysine is symboled HA, and the de-protonated form (basic form) of lysine is symboled A-.

The ...

Solution Summary

This solution contains step-by-step calculations to determine the protonation of lysine at pH 9.5 and 11. All formulas and workings are shown for better understanding.