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# ANOVA and Critical Thinking Analysis of a Drug

A DRUG IS DEVELOPED TO LOWER PULSE RATES. In order to obtain more consistent results that do not have confounding variables of gender, the drug is tested using males only. Given below are pulse rates for a placebo group, a group of men treated with Xynamine in 10 mg doses and a group of men treated with 20mg doses. Research finds that the adult males, pulse rates are normally distributed with a mean around 70 beats per min. and a SD of approx. 11 beats per min. Summary reports states the drug is effetive, based on this evidence. the placebo group has a mean pulse rate of 68.9, which is close to the value of 70 beats per min. for adult males in general, but the group treated with the 10 mg doses has a lower mean of 66.2 and the group treated with the 20mg doses has the lowest mean of 65.2

(1) Based on the results does it appear that the is sufficient evidence to support the claim that the drug lowers pulse rates?

(2) Are there serious problems with the design of the experiment?

(3) The project manager compared the post-treatment pulse rates for adult males. Is there a better way to measure the drugs effectiveness to lower pulse rates? How can I measure the overall validity of the experiment?

(4) Should this drug be approved based on the finding?

PLACEBO 10MG TREATMENT 20MG TREATMENT
GROUP GROUP GROUP
77 67 73
61 48 94
66 79 57
63 67 63
81 57 69
75 71 59
66 66 64
79 85 82
66 75 34
75 77 76
48 57 59
70 45 53

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ANALYSIS OF VARIANCE/ CRITICAL THINKING
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A NEW DRUG IS DEVELOPED TO LOWER PULSE RATES. In order to obtain more consistent results that do not have confounding variable of gender, the drug is tested using males only. Given below are pulse rates for a placebo group, a group of men treated with Xynamine in 10 mg doses and a group of men treated with 20mg doses. Research finds that the adult males, pulse rates are normally distributed with a mean around 70 beats per min. and a SD of approx. 11 beats per min. Summary reports states the drug is effective, based on this evidence. The placebo group has a mean pulse rate of 68.9, which is close to the value of 70 beats per min. for adult males in general, but the group treated with the 10 mg doses has a lower mean of 66.2 and the group treated with the 20mg doses has the lowest mean of 65.2

(1) Based on ...

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