I am confused on how to approach these free energy calculation problems. I have done some work but am not sure if I am on the correct path. I would appreciate a solution with explanations.© BrainMass Inc. brainmass.com October 10, 2019, 5:56 am ad1c9bdddf
4. The general principle is this--set up a Born-Haber cycle connecting the transformation of D-glucose to D-galactose and then divide the problem into 2 parts. Remember, the free energies are additive
So let us say convert D-glucose from a 0.0001 M solution to a 0.1 M solution.
The free energy change = RTln(C2/C1) = 2 x 298 x ln (0.1/0.0001) = 4.12 Kcal/mol @ 25°C
Convert this D-glucose at 0.1 M to D-galactose at 0.1 M then the change is given by -220.73 - (-219.22) = -1.51 Kcal/mol
This solution explains a series of free energy physical chemistry problems.