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Give a detailed mechanism for the reaction that occurs when ethyl methylmalonate CH3-CH(C=OOC2H5)2, acetone and 2-chloroacrylonitrile (CH2=CClCN) react in the presence of a base, to yield an epoxy compound CH3-C(EtOOC)2-CH2-C(NC)-O-C(CH3)2© BrainMass Inc. brainmass.com March 6, 2023, 1:21 pm ad1c9bdddf
Please find attached a mechanism detailing the solution to this problem...the key points are:
In the presence of a base the diester is deprotonated to form an enolate (which is ...
It provides the mechanism for the reaction that occurs when ethyl methylmalonate, acetone, and 2-chloroacrylonitrile react in the presence of a base. A Darzens reaction is analyzed.