Explore BrainMass

Explore BrainMass

    antigenic drift / antigenic shift

    This content was COPIED from BrainMass.com - View the original, and get the already-completed solution here!

    Using named examples compare and contrast viral evolution via antigenic drift and via antigenic shift. State which mechanism is most significant in terms of impact of human disease explaining your answers.

    © BrainMass Inc. brainmass.com October 10, 2019, 2:44 am ad1c9bdddf

    Solution Preview

    Consistent with Brainmass policies, the following solution is meant as a guide to assist you with the assignment, rather than a completed assignment for submission.
    Antigenic shift can only occur in viruses with multipartite genomes, i.e. genomes that consist of several copies of RNA that together make up the viral genome. One example is influenza virus, an orthomyxovirus consisting of eight negative sense copies of RNA. When a cell is infected with two different influenza viruses, usually one of human origin and one of avian origin, the eight molecules of viral RNA from each virus replicate independently. When these are packaged into new virus particles, one copy of each viral segment is chosen at random, and reassortment of the segments from the two ...

    Solution Summary

    This solution explains the difference between antigenic shift and antigenic drift in virus infections, and provides examples of both processes.