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Antibiotic development and resistance

Please look at the following websites to help find information and answer the following questions. I have read the the information and suppose I am just looking for "specific quotes" but think I may need someone to put it in simpler terms.

http://www.cdc.gov/getsmart/antibiotic-use/antibiotic-resistance-faqs.html
http://amrls.cvm.msu.edu/microbiology

1. Why is it easier to develop drugs to kill bacteria than viruses or protozoa?

2. Why are some antibacterial drugs only used on the skin?

3. How do microbes become resistant to antimicrobial control methods?

Solution Preview

"Antibiotics that kill bacteria" is kind superfluous, since by definition antibiotics ONLY kill bacteria. For questions number 1 and 2, the answers are not really in the website you mentioned. It needs a little more research into the subject. I am providing here a brief explanation to the questions and a guideline of how to address them. There are plenty of references on the internet and textbooks, as these are generally known facts. For question 3, I took it out of your second website, which is very comprehensive and you should try to review and understand the material as much as you can.

1. It is easier to develop drugs against bacteria since they are easy targets. Most of bacterial infections are extracellular, which means that they don't need to go into host cells to ...

Solution Summary

The solution discusses reasons why antibiotics are easier to develop compared to antivirals or anti-protozoa. It also discuss the usage of antibiotics topically, and describe possible mechanisms of how microbes acquire resistance to antimicrobials.

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