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    Relation between telomeres and aging

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    One aspect of aging appears to be related to telomeres. Every time a chromosome is duplicated in the S Phase of interphase, the ends of the chromosome (i.e. telomeres) unravel. This sets a limit of around 50 cell divisions before the chromosome unraveling effects genes. Explain the significance of this.

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    With a limit of 50 cell divisions, the number of times a cell divides will determine how long it can maintain normal cellular physiology. The fasted dividing cells, such as in the intestine, are replaced once a week, while other cells may divide a given number of times before entering a non-dividing state (e.g. neurons). As cells age and loose telomeric regions, they become ...

    Solution Summary

    Two short paragraphs explaining what telomeres are and how they relate to aging. Web references provided.