Purchase Solution

Determining paternity

Not what you're looking for?

Ask Custom Question

Please state whose daughter it is? How did you come up with that conclusion?

Purchase this Solution

Solution Summary

Detailed answer explaining how paternity can be established via VNTR analysis Web references provided.

Solution Preview

This problem uses VNTR (variable number tandem repeats) to establish paternity. Because of the variable nature of VNTRs (i.e. the copy number can be different from unrelated persons) a panel of them can be used to suggest family relation. While unrelated individuals may have the same VNTR at one loci the probability of a coincidental match decreased with the number of locus examined. In this manner a panel of VNTRs can act like a fingerprint. Because they are inherited the VNTRs will be a mixture of the VNTRs found in both parents. To examine these VNTRs you can perform RFLP (restriction fragment length polymorphism) where by you digest genomic DNA with a specific restriction enzyme and examine the different fragment lengths on a gel. With the advent of PCR and the availability of genome sequence PCR primers can be designed for specific VNTR loci. They can then be amplified by PCR and examined of a gel. The length of the PCR fragment will indicate the size of the repeat. By comparing a subjects pattern with those of potential parents relations can be established.

In this problem we are given the VNTR pattern for a claimed child, Liliana Pereya (#9), of Monica Grinspon and Claudio Ernesto Logares. We also have the VNTR pattern for a ...

Purchase this Solution

Free BrainMass Quizzes
Human Anatomy- Reproductive System

Do you know your reproductive anatomy?


Basics in biology

Understanding the Musculoskeletal system

Introduce and understand basic information how the skeletal system and muscular system work in close concert with one another. And how their interaction between muscle and bone, as they work together to allow us movement.

The Transfer of Energy in an Ecosystem

This quiz will assess your knowledge of how energy is transferred in an ecosystem and the different levels of trophic organization.

How Much Do You Know About Genetic Inheritance?

Most of us studied the basics of dominant and recessive genes at some point. However, genetics are much more complicated than this. How far beyond the basics does your knowledge go?