The MN blood group in humans is under the control of a pair of codominant alleles, LM
and LN. In a group of 556 individuals, the following genotypic frequencies are found:
(a) Calculate the frequency of the LM and LN alleles.
(b) Test (using the Chi-squared test) whether the genotype frequencies conform to the
MM MN NN Sum
First determine the frequency of M using the following equation: p2+1/2(2pq). Substitute the numbers from each of the above observed values and solve for p.
.30=1/2(.50) =.55 therefore P=.55
To get pq simply multiply the above values. To get 2 pq multiply pq by 2.
These solutions are the expected frequencies for the alleles if the population ...
This solution will explain how to use a chi-squared test to determine whether or not the blood groups of a population are in Hardy-Weinberg equilibrium. A link to a similiar example problem is included.