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    Arranging clones in an overlapping group

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    Geneticists working on the Human Genome Project focused on one band of chromosome 11. From this region they had a collection of eight cloned fragments (clones 1-8). They also determined that seven sequence-tagged sites (STSs a-g) were distributed among these clones, suggesting clone overlap. The STS distribution appears in the table below.

    Arrange these clones into an overlapping group (contig) showing the regions of overlap and the positions of the STSs.

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    Solution Preview

    To restate the problem first, what we have here is a region of DNA with 7 separate sequences in it, labeled a-g. We've made 8 clones of this stretch of DNA, each clone containing at ...

    Solution Summary

    The expert examines arranging clones in an overlapping group.