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    The autoradiogram below shows the genomic DNA fragments produced by digesting genomic DNA with the restriction enzyme Mst II and probing the membrane with a DNA probe specific for the beta globin chain gene of hemoglobin. The parents are C and D, and the children are E and F. Hb S indicates a mutated gene leading to the sickle cell condition. Hb A indicates normal hemoglobin.

    Please see attachment (take note: HbS goes with first row; HbS with second row)

    a) Does child F have sickle cell anemia
    b) Why does child E have only one band showing on the gel?

    © BrainMass Inc. brainmass.com October 10, 2019, 6:03 am ad1c9bdddf


    Solution Preview

    A. Yes child F does have the mutated gene that leads to sickle cell anemia. ...

    Solution Summary

    This solution contains an overview of the autoradiogram of a child.